Aspirin

Tɛmplet:Infobox drug/title
Names
Pronunciation	acetylsalicylic acid /əˌsiːtəlˌsælɪˈsɪlɪk/
Trade names	Bayer Aspirin, many others
Other names	Tɛmplet:Infobox drug/localINNvariants
	IUPAC name 2-Acetoxybenzoic acid;
Clinical data
Main uses	Pain, fever, prevent heart disease
Side effects	Upset stomach, stomach ulcers, stomach bleeding, worsening asthma
WHO AWaRe	Script error: No such module "WDfetch".
Pregnancy; category	Tɛmplet:Infobox drug/pregnancy category
Routes of; use	By mouth, rectal, lysine acetylsalicylate may be given intravenously or intramuscularly
Defined daily dose	3 g (by mouth or rectum); 1 g (by injection) for pain; 1 tablet (irrespective of strength) for clot prevention
External links
AHFS/Drugs.com	Tɛmplet:Drugs.com
MedlinePlus	a682878
Legal
[[Regulation of therapeutic goods \|Tɛmplet:Engvar data]]	Tɛmplet:Infobox drug/licence
Legal status	Tɛmplet:Infobox drug/legal status
Pharmacokinetics
Bioavailability	80–100%
Protein binding	80–90%
Metabolism	Liver, (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.
Elimination half-life	Dose-dependent; 2 h to 3 h for low doses (100 mg or less), 15 h to 30 h for large doses.
Excretion	Urine (80–100%), sweat, saliva, feces
Identifiers
CAS Number	Tɛmplet:Infobox drug/formatCASnumber; Tɛmplet:Infobox drug/formatCASnumber;
PubChem CID	Tɛmplet:Infobox drug/formatPubChemCID; Tɛmplet:Infobox drug/formatPubChemCID;
PubChem SID	Tɛmplet:Infobox drug/formatPubChemSID; Tɛmplet:Infobox drug/formatPubChemSID;
IUPHAR/BPS	Tɛmplet:Infobox drug/formatIUPHARBPS; Tɛmplet:Infobox drug/formatIUPHARBPS;
DrugBank	Tɛmplet:Infobox drug/formatDrugBank; Tɛmplet:Infobox drug/formatDrugBank;
ChemSpider	Tɛmplet:Infobox drug/formatChemSpider; Tɛmplet:Infobox drug/formatChemSpider;
UNII	Tɛmplet:Infobox drug/formatUNII; Tɛmplet:Infobox drug/formatUNII;
KEGG	Tɛmplet:Infobox drug/formatKEGG; Tɛmplet:Infobox drug/formatKEGG;
ChEBI	Tɛmplet:Infobox drug/formatChEBI; Tɛmplet:Infobox drug/formatChEBI;
ChEMBL	Tɛmplet:Infobox drug/formatChEMBL; Tɛmplet:Infobox drug/formatChEMBL;
NIAID ChemDB	Tɛmplet:Infobox drug/formatChemDBNIAID; Tɛmplet:Infobox drug/formatChemDBNIAID;
PDB ligand	Tɛmplet:Infobox drug/formatPDBligand; Tɛmplet:Infobox drug/formatPDBligand;
CompTox Dashboard (EPA)	Tɛmplet:Infobox drug/formatCompTox; Tɛmplet:Infobox drug/formatCompTox;
ATC code	Tɛmplet:Infobox drug/formatATC; Tɛmplet:Infobox drug/formatATC;
Chemical and physical data
Formula	Tɛmplet:Infobox drug/chemical formula
Molar mass	Tɛmplet:Chem molar mass
3D model (JSmol)	Tɛmplet:Infobox drug/formatJmol; Tɛmplet:Infobox drug/formatJmol;
Density	1.40 g/cm3
Melting point	136 °C (277 °F)
Boiling point	140 °C (284 °F) (decomposes)
Solubility in water	3g/L
	SMILES O=C(C)Oc1ccccc1C(=O)O;
	InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)Tɛmplet:Stdinchicite; Key:BSYNRYMUTXBXSQ-UHFFFAOYSA-NTɛmplet:Stdinchicite;

Tɛmplet:Infobox drug/maintenance categories

Aspirin bɛ ni lahi mi tila shɛli acetylsalicylic acid (ASA) la nyɛla tila shɛli din tibiri biɛrim ningbuŋ biili nti pahi inflammation ^[8]

References

1 2 Aspirin. American Society of Health-System Pharmacists (June 6, 2016).
↑ ACETYLSALICYLIC acid = ASPIRIN = ASA oral - Essential drugs.
↑ WHOCC - ATC/DDD Index.
↑ WHOCC - ATC/DDD Index.
1 2 Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more. Medscape Reference. WebMD.
1 2 3 Brayfield, A:Aspirin. Martindale: The Complete Drug Reference. Pharmaceutical Press (14 January 2014).
↑ Tɛmplet:RubberBible92nd
↑ Aspirin. American Society of Health-System Pharmacists (June 6, 2016).

[AHSF2016-1] 1 2 Aspirin. American Society of Health-System Pharmacists (June 6, 2016).

[MSF2020-2] ACETYLSALICYLIC acid = ASPIRIN = ASA oral - Essential drugs.

[who-3] WHOCC - ATC/DDD Index.

[who1-4] WHOCC - ATC/DDD Index.

[MSR-5] 1 2 Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more. Medscape Reference. WebMD.

[MD-6] 1 2 3 Brayfield, A:Aspirin. Martindale: The Complete Drug Reference. Pharmaceutical Press (14 January 2014).

[b92-7] Tɛmplet:RubberBible92nd

[AHSF20162-8] Aspirin. American Society of Health-System Pharmacists (June 6, 2016).

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